abstract：PURPOSE OF REVIEW:International bodies acknowledge that palliative care principles and access to palliative care services should be offered to persons living with and dying from advanced illness such as heart failure. Without an appropriately trained workforce, however, appropriate goals of care and associated reductio...

journal_title：Current opinion in supportive and palliative care

authors： Millerick Y,Armstrong I

更新日期：2015-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients' autonomy is seen as a major issue in modern medicine but requires the ability to understand and rate an issue without being influenced by others. However, near the end of life, patients often decide considering the consequences for their relatives. RECENT FINDINGS:Our study results and rece...

journal_title：Current opinion in supportive and palliative care

authors： Marx G,Owusu Boakye S,Jung A,Nauck F

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In the last 10 years, metastatic castration-resistant prostate cancer (mCRPC) treatment has completely changed. Several new agents have been shown to increase mCRPC patients' overall survival. The importance to define castration-resistant prostate cancer as metastatic and to enable earlier detection o...

journal_title：Current opinion in supportive and palliative care

authors： Beauregard JM,Pouliot F

更新日期：2014-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The serotonergic system has long been linked to migraine but recent studies highlight how much is still unclear about this link. And recent data add to the uncertainty of where/how triptans act and why they are headache specific. RECENT FINDINGS:Markers of 5HT levels in the brains of migraine patient...

journal_title：Current opinion in supportive and palliative care

authors： Dussor G

更新日期：2014-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Sequential anthracycline/taxane regimens are routinely used as neoadjuvant therapy (NAT) for locally advanced breast cancer. Unfortunately, the majority of patients do not achieve a pathological complete response (pCR). Efforts to improve pCR rates include the addition of novel targeted agents. The pu...

journal_title：Current opinion in supportive and palliative care

authors： Wilson S,Chia S

更新日期：2014-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Many health professionals still believe that opioids shorten the lifespan of patients. This situation implies that the ethical doctrine of double effect is often invoked to justify their use in extreme circumstances. The objective of this study is to revise the evidence existing in the recently publis...

journal_title：Current opinion in supportive and palliative care

authors： López-Saca JM,Guzmán JL,Centeno C

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In the past 20 years, several papers have been published concerning healthcare transition from pediatric after-care to long-term follow-up in adult health service for childhood cancer survivors. Initially, the papers were optimistic and included guidelines and models of care. However, after this optim...

journal_title：Current opinion in supportive and palliative care

authors： Frey E,van der Pal H

更新日期：2013-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Providing palliative care in Japan is one of the most important health issues. Understanding palliative care delivery systems of other countries is useful when developing and modifying palliative care systems worldwide. This review summarizes the current status of palliative care in Japan, focusing on...

journal_title：Current opinion in supportive and palliative care

authors： Morita T,Kizawa Y

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:There are increasing numbers of adults with congenital heart disease (CHD) and these patients remain at long-term risk of complications and premature death. This review focuses on the changing picture of adult CHD with more complex patients surviving, the challenges of balancing life-prolonging interv...

journal_title：Current opinion in supportive and palliative care

authors： Bowater SE,Speakman JK,Thorne SA

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To emphasize that the management of wounds represents a significant component within the overall supportive and palliative care of patients with advanced illness. It is also intended to clarify the linguistics that are commonly used around patients with wounds. RECENT FINDINGS:New paradigms for wound...

journal_title：Current opinion in supportive and palliative care

authors： Maida V

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Mixed methods research designs have been recognized as important in addressing complexity and are recommended particularly in the development and evaluation of complex interventions. This article reports a review of studies in palliative care published between 2010 and March 2012 that combine qualitat...

journal_title：Current opinion in supportive and palliative care

authors： Seymour J

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The balance between the rates of protein synthesis and protein degradation governs the maintenance of muscle mass in the body. The main purpose of this review is to highlight the latest understanding of the various pathways that maintain this balance between muscle atrophy and hypertrophy. RECENT FIN...

journal_title：Current opinion in supportive and palliative care

authors： Banerjee A,Guttridge DC

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the advances in trial methodology and presents new methodologies to meet some of the challenges of conducting trials in a palliative care setting. To describe why this review is timely and relevant. RECENT FINDINGS:This review discusses the process required to conduct trials of ...

journal_title：Current opinion in supportive and palliative care

authors： Davis MP,Mitchell GK

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe a new strategy that aimed to facilitate opioid prescription for better pain management. RECENT FINDINGS:The International Association of Hospice and Palliative Care recently develop a single prescription package (drugs and dosing) with one opioid, one laxative, and one antiemetic for the ...

journal_title：Current opinion in supportive and palliative care

authors： Vignaroli E,Wenk R

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Bone metastases in prostate cancer are often the cause of significant morbidity in patients with castrate-resistant disease, and several studies have shown significant pain palliation with systemic radionuclide treatment. The purpose of this review is to discuss the place of radionuclides in the dynam...

journal_title：Current opinion in supportive and palliative care

authors： Vengalil S,O'Sullivan JM,Parker CC

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The study provides a review of current evidence about the role of complex nonpharmacological strategies in managing the multidimensional components of the breathlessness experience for individuals with life-limiting conditions. RECENT FINDINGS:Evidence continues to demonstrate the significant impact ...

journal_title：Current opinion in supportive and palliative care

authors： Yates P,Zhao I

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The review is based on a Medline literature search using key words relating to male urogenital/pelvic pain for the years 2009-2011. RECENT FINDINGS:The review covers those studies relating to cause, ongoing mechanisms and treatments. SUMMARY:The review highlights that the patients are often polysymp...

journal_title：Current opinion in supportive and palliative care

authors： Baranowski AP

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes recent developments in the management of gastrointestinal symptoms experienced by cancer patients and provides a framework for education, assessment and monitoring, and treatment. RECENT FINDINGS:Although many viable treatment options exist, gastrointestinal symptoms - particul...

journal_title：Current opinion in supportive and palliative care

authors： Rangwala F,Zafar SY,Abernethy AP

更新日期：2012-03-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize developments in the management of brain metastases over the past decade. RECENT FINDINGS:A few randomized trials have been published during the past decade examining the use of whole brain radiotherapy (WBRT) and radiosurgery (SRS) boost versus WBRT alone. Other recent trials have been p...

journal_title：Current opinion in supportive and palliative care

authors： Tsao MN,Khuntia D,Mehta MP

更新日期：2012-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Cross-sectional (C-S) imaging is now commonly used to measure body composition in clinical studies. This review highlights the advantages, limitations and suggested future directions for this technique. RECENT FINDINGS:Current understanding of C-S imaging reproducibility, tissue identification and se...

journal_title：Current opinion in supportive and palliative care

authors： MacDonald AJ,Greig CA,Baracos V

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To understand the mechanisms of muscle wasting and how inhibiting myostatin signaling affects them. RECENT FINDINGS:Myostatin signaling is critical for the understanding of the pathogenesis of muscle wasting as blocking signaling mitigates muscle losses in rodent models of catabolic diseases includin...

journal_title：Current opinion in supportive and palliative care

authors： Han HQ,Mitch WE

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:RANK ligand (RANKL) plays a central role in the cancer-induced bone destruction that results from bone metastasis. The RANKL inhibitor denosumab was recently approved for the prevention of skeletal-related events (SREs) in patients with bone metastases from solid tumors. This review summarizes recent ...

journal_title：Current opinion in supportive and palliative care

authors： Lipton A,Jacobs I

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Agents used for systemic chemotherapy can alter normal bone homeostasis through mechanisms that affect both osteoblast and osteoclast function. The identification of those agents that influence maintenance of the bone-remodeling compartment is an important component of the drug development and testing...

journal_title：Current opinion in supportive and palliative care

authors： Silbermann R,Roodman GD

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:It is difficult to hold an organized view of psychological research related to chronic pain. There are many different theories and variables and the volume of literature is vast. The purpose of this review is to highlight some key trends in this research in 2010. RECENT FINDINGS:We conducted a search...

journal_title：Current opinion in supportive and palliative care

authors： McCracken LM,Thompson M

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the most recent studies that examine the efficacy of psychostimulants for the relief of symptoms such as asthenia and depression in cancer patients. RECENT FINDINGS:Although most research to date has focused on the use of methylphenidate for the relief of symptoms such as astheni...

journal_title：Current opinion in supportive and palliative care

authors： Portela MA,Rubiales AS,Centeno C

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Pelvic pain is a common complaint of women that is frequently poorly managed. This review considers the current understanding of the mechanisms of pain perception and the development of chronic pain in the context of three gynaecological pain conditions. Recent advances in the management of these cond...

journal_title：Current opinion in supportive and palliative care

authors： Vincent K

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Determining which palliative interventions are appropriate within and between groups remains difficult because of the lack of prospective studies and heterogeneity in dyspnoea context, assessment and reporting. This review presents an evolution of dyspnoea theories, summarizes literature published dur...

journal_title：Current opinion in supportive and palliative care

authors： Williams M

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the psychosocial support of people affected by cancer anorexia, drawing on recent publications. RECENT FINDINGS:Recent studies describe the problem of distress in response to cancer anorexia. There are propositions of appropriate support and calls for the development of psychosocial interv...

journal_title：Current opinion in supportive and palliative care

authors： Hopkinson JB

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite recognition that opioids alleviate dyspnea in chronic obstructive pulmonary disease, many clinicians remain reluctant to use them outside of the final days of life. This article defines the term 'opioid responsiveness' as it pertains to dyspnea, and poses that it may be possible to predict mor...

journal_title：Current opinion in supportive and palliative care

authors： Horton R,Rocker G,Currow D

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Dyspnea is the most common symptom in interstitial lung disease, yet little is known about its management. This review summarizes the available evidence for the treatment of dyspnea in interstitial lung disease. RECENT FINDINGS:The management of dyspnea in interstitial lung disease remains a challeng...

journal_title：Current opinion in supportive and palliative care

authors： Ryerson CJ,Collard HR,Pantilat SZ

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Gastrointestinal toxicity during chemotherapy is frequent. Symptomatic therapies for gastrointestinal toxicity, which do not address the underlying cause, may result in inadequate symptom control. With advances in curative treatment regimens, it becomes more important to minimize treatment toxicity wh...

journal_title：Current opinion in supportive and palliative care

authors： Andreyev HJ

更新日期：2010-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with heart failure seem particularly suited to palliative care having needs that fall within the prototypical palliative care domains. Despite this there is still much debate as to who should respond to these needs and when. RECENT FINDINGS:Since the early 1990s many studies have been publis...

journal_title：Current opinion in supportive and palliative care

authors： O'Leary N

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the role of lung volume reduction surgery (LVRS) for the management of refractory dyspnea and other debilitating conditions in patients with chronic obstructive pulmonary disease. Recent studies, including a randomized trial comparing LVRS to medical therapy, are analyzed. RECEN...

journal_title：Current opinion in supportive and palliative care

authors： Shah AA,D'Amico TA

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes recent developments in the palliative management of gastrointestinal symptoms experienced by advanced cancer patients and provides a framework for detailing that encompasses education, assessment and monitoring, and treatment. RECENT FINDINGS:Although many viable treatment opti...

journal_title：Current opinion in supportive and palliative care

authors： Abernethy AP,Wheeler JL,Zafar SY

更新日期：2009-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review compares the catabolic actions of tumour necrosis factor-alpha (TNF-alpha) and proteolysis-inducing factor (PIF) and their involvement in human cancer cachexia. RECENT FINDINGS:TNF-alpha has a direct catabolic effect on skeletal muscle and adipose tissue, whereas PIF only has an effect on...

journal_title：Current opinion in supportive and palliative care

authors： Tisdale MJ

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent advances in the diagnosis and treatment of many types of cancers have prolonged and improved the quality of life for cancer patients. With increased survival, metastatic spinal lesions are becoming much more of a functional and clinical problem. RECENT FINDINGS:Percutaneous vertebral augmentat...

journal_title：Current opinion in supportive and palliative care

authors： Siemionow K,Lieberman IH

更新日期：2008-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to consolidate the literature around pain assessment and management in older adults with dementia and to make recommendations for future research and practice developments. This review is provided following the introduction of guidelines for the assessment of pain that wer...

journal_title：Current opinion in supportive and palliative care

authors： Schofield P

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Constipation is a common symptom in palliative care patients that can generate considerable suffering due to both unpleasant physical symptoms and psychological preoccupations that may arise. There is uncertainty about the choice from varying recommendations for management of constipation and a varyin...

journal_title：Current opinion in supportive and palliative care

authors： Clemens KE,Klaschik E

更新日期：2008-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite its increasing prevalence and high mortality risk, heart failure is widely regarded as 'treatable'. Aggressive measures are employed even in its end stages. This review explores the clinical characteristics of heart failure, patterns of clinician response, and new data that may help to surmoun...

journal_title：Current opinion in supportive and palliative care

authors： Stuart B

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Cachexia, also known as disease-associated wasting, is an important factor in the mortality of many patients with diseases such as cancer, as well as renal and congestive heart failure. Yet the syndrome is not yet well defined, making diagnosis difficult and often subjective on the part of the physici...

journal_title：Current opinion in supportive and palliative care

authors： Fletcher AL,Marks DL

更新日期：2007-12-01 00:00:00